Jurnal Kesehatan

EFFECTIVENESS OF PERSONAL SAFETY SKILLS TRAINING AS AN EFFORT TO PREVENT SEXUAL VIOLENCE IN ADOLESCENTS

Elisa Christiana — 2025-03-31

Background: Sexual violence is sexual behavior that can negatively affect a person's health and quality of life. Indonesia has entered the “sexual violence emergency” phase in the past decade after experiencing a significant spike in cases each year. The impact of victims of sexual violence usually appears several years after the violence occurs such as physical and psychological damage.

Objective: to determine the effectiveness of respondents' knowledge before and after training to determine the effectiveness of Personal Safety Skills on the ability to prevent sexual violence.

Methods: The study used experimental research with a quasi experimental design of one group pretest posttest design. The population was 17 students of SMP Muhammadiyah 1 Sampang with purposive sampling technique. Data analysis using non-parametric statistical techniques with differential t-test.

Results: The results of the paired t test analysis with a p value = 0.001 so that p <0.05 this shows a significant difference between the pre-test and post-test values.

Conclusion: Personal Safety Skill is effective to improve the ability to prevent sexual violence in adolescents before training and after training. This shows that children are able to absorb the information provided during training

A Systematic Literature Review of the Effectiveness of Mindfulness-Based Cognitive Therapy on Depression Among Older People

Helena Patricia — 2025-03-31

The worldwide population of older people is rising rapidly, with projections suggesting that by 2050, persons aged 60 and over will represent 22% of the entire population. Age-related outcomes are significantly exacerbated by frailty, susceptibility, and an elevated risk of depression. Mindfulness-Based Cognitive Therapy (MBCT) has become a feasible therapeutic approach, integrating cognitive therapy with mindfulness techniques. This review systematically assesses the efficacy of MBCT in alleviating depression in the older population. This review adheres to PRISMA criteria. Seven databases (Medline, Scopus, ClinicalKey for Nursing, Ebsco, Web of Science, Cochrane Library, and Grey Literature) were examined from 2017 to 2022. Three keywords utilized were depression, elderly individuals, and MBCT. The quality of the studies was assessed using the Joanna Briggs Institute's (JBI) critical appraisal tool. Eleven studies were incorporated for the review. Research demonstrates that MBCT is advantageous in alleviating depression among the older population. This review indicates that MBCT is a potential alternative therapy for older individuals experiencing depression. It is imperative to emphasise that future research must demonstrate enhanced structural quality and require larger sample sizes.

Improvement IL -10 and Reactive Oxygen Species (ROS) in HIV patients : Narrative Review

Indra Franajayakk — 2025-03-31

Background: Infection Human Immunodeficiency Virus (HIV) is still become problem scary health for world community . This virus infection causes a bunch symptom disease characterized by with weakening system immunity body . A collection of symptoms This known with designation Acquired Immune Deficiency Syndrome (AIDS). Consequence the decline system immunity , HIV sufferers will prone to For caught various disease infections that can have fatal consequences.

Objective: For know How improvement IL-10 and Reactive Oxygen Species (ROS) levels in HIV patients .

Research methods: This use Narrative Review design . Articles searched from Google Scholar, PubMed, Science Direct, and EMBASE/ Elviser with use relevant keywords , then chosen based on criteria that have been set , and objectives study .

Results: Increased levels of IL-10 and Reactive Oxygen Species (ROS) in patients results in a decrease in the immune system, this is characterized by increased virus replication, deactivation macrophages and depletion of the number of lymphocytes, so that the progression of the infection towards AIDS can occur.

Conclusion: HIV infection causes the occurrence dysfunction mitochondria and enhancement production Reactive Oxygen Species (ROS) in cells CD4 ⁺T lymphocytes. Various viral proteins, such as the envelope proteins Gp120, Tat, Nef and Vpr , are able to increase ROS production through various different pathways. The increase in ROS that occurs can increase mRNA expression through activation Nuclear Factor Kappa B ( NFκB ), increased IL-10 mRNA expression ultimately will increase IL-10 levels